Sant'Orsola Church was built for the 'Compagnia di Sant'Orsola' (Brotherhood of Saint Ursula), a group of believers which was founded in 1564 in the neighbouring church of Santi Quaranta Martiri Pisani al Casalotto.
The church was open to the public in 1662. The nave, and maybe the entire building, was designed by Giacomo Amato. In 1672 a beautification work started. During this period the building was decorated with stuccos and paintings. In the following century another beautification work was made. As a result of these actions, the church houses several artworks of important Sicilian artists.
References:The Clementinum is a historic complex of buildings in Prague. Until recently the complex hosted the National, University and Technical libraries, the City Library also being located nearby on Mariánské Náměstí. The Technical library and the Municipal library have moved to the Prague National Technical Library at Technická 6 since 2009. It is currently in use as the National Library of the Czech Republic.
Its history dates from the existence of a chapel dedicated to Saint Clement in the 11th century. A Dominican monastery was founded in the medieval period, which was transformed in 1556 to a Jesuit college. In 1622 the Jesuits transferred the library of Charles University to the Klementinum, and the college was merged with the University in 1654. The Jesuits remained until 1773, when the Klementinum was established as an observatory, library, and university by the Empress Maria Theresa of Austria.