A church at the site of current San Francesco, dedicated to St John, was present since perhaps the seventh-century, since nearby Christian burial appear to date from then. In around 1244, the church began to be administered by priests from the Cathedral of Acqui. Around 1410, it became associated with the Franciscan order, and rebuilt and rededicated. The convent was suppressed in 1802, and the church was affiliated with the Confraternity of San Giuseppe, who briefly changed the name of the church. In 1824, the Franciscans returned, and they rebuilt the church in a neoclassic-style, adding the Facade, under the design of Ferraris in 1835, completed in 1854.
Parts of the church are ancient. The bell-tower and apse date to the 15th century. But other parts reflect refurbishments along the centuries, including the 19th-century reconstruction. The broad brick facade (1835–1854) shows eclectic styles with a triangular lower tympanum and monumental order pilasters.
The interior houses an Immaculate Conception by il Moncalvo; an Adoration of the Magi by Raffael Angelo Soleri; and a Madonna and Child with Saint Francis and Antony of Padua by Pietro Beccaria. The ceilings were frescoed by the 19th-century painter Pietro Ivaldi, detto il Muto di Toleto.
References:The Clementinum is a historic complex of buildings in Prague. Until recently the complex hosted the National, University and Technical libraries, the City Library also being located nearby on Mariánské Náměstí. The Technical library and the Municipal library have moved to the Prague National Technical Library at Technická 6 since 2009. It is currently in use as the National Library of the Czech Republic.
Its history dates from the existence of a chapel dedicated to Saint Clement in the 11th century. A Dominican monastery was founded in the medieval period, which was transformed in 1556 to a Jesuit college. In 1622 the Jesuits transferred the library of Charles University to the Klementinum, and the college was merged with the University in 1654. The Jesuits remained until 1773, when the Klementinum was established as an observatory, library, and university by the Empress Maria Theresa of Austria.