Monteserico Castle is situated on a hill in a strategic position for controlling commercial traffic on the Appian Way that passed nearby. First documented in 1041, the year of a famous battle between the Byzantines and the Normans, it became a domus during the Swabian period and a royal farmstead under the Angevins. The Monteserico Castle communicated with the Garagnone Castle and the Gravina Castle (commissioned by Frederick II) through signal torches to alert of approaching enemies.
Destroyed in the early 1500s, it underwent restoration in several phases from the 18th to the 19th century and has recently been the subject of restoration efforts.
In 1989, the municipality of Genzano di Lucania acquired ownership of the building.
The first written record of church in Danmark locality date back to the year 1291. Close to the church are several stones with a Christian text and cross inscribed. The oldest parts of the present red-brick church are from the 1300s. In the late 1400s the church was enlarged to the appearance it has today. The church has been modified both internally and externally several times, among other things after the fires in 1699 and 1889. There are lot of well-preserved mural paintings in the walls.