Sant'Anastasia curch was built between the late 3rd and early 4th century, possibly by a Roman woman named Anastasia. The church is listed under the titulus Anastasiae in the acts of the 499 synod. Later the church was entitled to the martyr with the same name, Anastasia of Sirmium.
The church was restored several times: Pope Damasus I (366-383), Pope Hilarius (461-468), Pope John VII (705-707), Pope Leo III (795-816), and Pope Gregory IV (827-844). The current church dates back to the 17th century restoration commissioned by Pope Urban VII.
Traditionally, the church is connected to the cult of St Jerome, who possibly celebrated mass here. The saint is depicted over the altar, by Domenichino.
The last restoration, after the restoration during the papacy of Sixtus IV, occurred in 1636, when the facade, with lower doric and upper ionic order, was reconstructed in 1636, after the cyclone of 1634. The nave recycles antique columns. The ceiling is frescoed with a martyrdom of the saints (1722) by Michelangelo Cerruti.
The chapel to the right, has a painting of St. John the Baptist by Pier Francesco Mola. The right transept has a painting of S.Toribio (1726) by Francesco Trevisani. The high altar has a Nativity by Lazzaro Baldi and below the altar is a statue of Saint Anastasia by Ercole Ferrata. It clearly shows the influence of Bernini's Beata Ludovica Albertoni. The left transept has a Madonna of the Rosary by Baldi, and the tomb of Cardinal and philologist Angelo Mai by the late neoclassical sculptor Giovanni Maria Benzoni. The last chapel to the left, by Domenichino depicts a St. Jerome. The other chapel has a Ss.Giorgio e Publio by Etienne Parrocel.
References:The Jan Hus Memorial stands at one end of Old Town Square. The huge monument depicts victorious Hussite warriors and Protestants who were forced into exile 200 years after Hus, and a young mother who symbolises national rebirth. The monument was so large that the sculptor designed and built his own villa and studio where the work could be carried out. It was unveiled in 1915 to commemorate the 500th anniversary of Jan Hus' martyrdom. The memorial was designed by Ladislav Šaloun and paid for solely by public donations.
Born in 1369, Hus became an influential religious thinker, philosopher, and reformer in Prague. He was a key predecessor to the Protestant movement of the sixteenth century. In his works he criticized religious moral decay of the Catholic Church. Accordingly, the Czech patriot Hus believed that mass should be given in the vernacular, or local language, rather than in Latin. He was inspired by the teachings of John Wycliffe.