Sant'Anastasia curch was built between the late 3rd and early 4th century, possibly by a Roman woman named Anastasia. The church is listed under the titulus Anastasiae in the acts of the 499 synod. Later the church was entitled to the martyr with the same name, Anastasia of Sirmium.
The church was restored several times: Pope Damasus I (366-383), Pope Hilarius (461-468), Pope John VII (705-707), Pope Leo III (795-816), and Pope Gregory IV (827-844). The current church dates back to the 17th century restoration commissioned by Pope Urban VII.
Traditionally, the church is connected to the cult of St Jerome, who possibly celebrated mass here. The saint is depicted over the altar, by Domenichino.
The last restoration, after the restoration during the papacy of Sixtus IV, occurred in 1636, when the facade, with lower doric and upper ionic order, was reconstructed in 1636, after the cyclone of 1634. The nave recycles antique columns. The ceiling is frescoed with a martyrdom of the saints (1722) by Michelangelo Cerruti.
The chapel to the right, has a painting of St. John the Baptist by Pier Francesco Mola. The right transept has a painting of S.Toribio (1726) by Francesco Trevisani. The high altar has a Nativity by Lazzaro Baldi and below the altar is a statue of Saint Anastasia by Ercole Ferrata. It clearly shows the influence of Bernini's Beata Ludovica Albertoni. The left transept has a Madonna of the Rosary by Baldi, and the tomb of Cardinal and philologist Angelo Mai by the late neoclassical sculptor Giovanni Maria Benzoni. The last chapel to the left, by Domenichino depicts a St. Jerome. The other chapel has a Ss.Giorgio e Publio by Etienne Parrocel.
References:Sigmaringen Castle was first mentioned in the year 1077 in the chronicles of Petershausen monastery. The oldest parts of the castle are concealed beneath the alterations made during the 17th and the 19th centuries. The secret of the earliest settlement built on this defendable rock will never be fully revealed: large-scale excavation work would be necessary, which the extensive land development renders impossible. Judging from the many Roman remains unearthed in the area around Sigmaringen, the 12th century keep known as the 'Roman Tower' could be traced back to a Roman predecessor.
The castle remains that have been preserved (gate, great hall and keep) date back to the Staufer period around 1200. The castle remains were integrated into subsequent buildings. The foundations of the castle buildings are to a large extent identical to the surrounding castle wall.
These remains give us a good idea of how the castle might have looked during the 12th century.