Sant'Anastasia curch was built between the late 3rd and early 4th century, possibly by a Roman woman named Anastasia. The church is listed under the titulus Anastasiae in the acts of the 499 synod. Later the church was entitled to the martyr with the same name, Anastasia of Sirmium.
The church was restored several times: Pope Damasus I (366-383), Pope Hilarius (461-468), Pope John VII (705-707), Pope Leo III (795-816), and Pope Gregory IV (827-844). The current church dates back to the 17th century restoration commissioned by Pope Urban VII.
Traditionally, the church is connected to the cult of St Jerome, who possibly celebrated mass here. The saint is depicted over the altar, by Domenichino.
The last restoration, after the restoration during the papacy of Sixtus IV, occurred in 1636, when the facade, with lower doric and upper ionic order, was reconstructed in 1636, after the cyclone of 1634. The nave recycles antique columns. The ceiling is frescoed with a martyrdom of the saints (1722) by Michelangelo Cerruti.
The chapel to the right, has a painting of St. John the Baptist by Pier Francesco Mola. The right transept has a painting of S.Toribio (1726) by Francesco Trevisani. The high altar has a Nativity by Lazzaro Baldi and below the altar is a statue of Saint Anastasia by Ercole Ferrata. It clearly shows the influence of Bernini's Beata Ludovica Albertoni. The left transept has a Madonna of the Rosary by Baldi, and the tomb of Cardinal and philologist Angelo Mai by the late neoclassical sculptor Giovanni Maria Benzoni. The last chapel to the left, by Domenichino depicts a St. Jerome. The other chapel has a Ss.Giorgio e Publio by Etienne Parrocel.
References:The Walls of Constantinople are a series of defensive stone walls that have surrounded and protected the city of Constantinople (today Istanbul) since its founding as the new capital of the Roman Empire by Constantine the Great. With numerous additions and modifications during their history, they were the last great fortification system of antiquity, and one of the most complex and elaborate systems ever built. They were also the largest and strongest fortification in both the ancient and medieval world.
Initially built by Constantine the Great, the walls surrounded the new city on all sides, protecting it against attack from both sea and land. As the city grew, the famous double line of the Theodosian Walls was built in the 5th century. Although the other sections of the walls were less elaborate, they were, when well-manned, almost impregnable for any medieval besieger.